Redefining “Community”: From Niche to Next-Generation Performance and Scale

Published Nov. 10, 2025 | 4 Minute Read

For years, the word “community” in the health space has been code for “niche”—a valuable, high-quality corner, perhaps, but one that lacks the scale to truly move the needle at a large scale. At Health Union, we’re changing that narrative entirely.

We’ve not only built the best, most engaging, and largest network of patient communities in the industry, but we’ve successfully leveraged that power to deliver unrivaled performance for our partners, proving that high quality and massive scale don’t have to be mutually exclusive. We are the first community-based activation company that has figured out how to take the high-quality, high-intent patients and actions within our communities and deliver those audiences at scaleeverywhere.

The Recipe for Community-Driven Success

How have we managed to transform the perception of community and deliver top-of-plan performance across every key metric, from qualified reach and cost efficiencies to conversions? It’s been a deliberate, intentional focus over our past two years of transformation, built on a foundation of proprietary data and cutting-edge technology.

  • Proprietary First-Party Data: Our success starts with the millions of data points collected directly from real people in our 53 communities. This data comes from authentic engagement—content consumption, polls, forum discussions, and large-scale surveys—not just claims data, which can be outdated and doesn’t cover the full spectrum of a patient’s intent. This gives us a crucial competitive edge.
  • The ILLUMINÉ Data Engine: We’ve invested in an industry-leading tech stack and the best people to bring our vision to life. The result is our data engine, ILLUMINÉ, which translates those millions of first-party (1P) data points into privacy-safe audiences in real time, enabling us to retarget the patients in our communities at scale and reach additional highly relevant patient audiences.
  • Real-Time, Predictive Targeting: Unlike targeting based on past actions, our method is based on what patients are doing now—real signals that help us predict what they are going to do next in their health journey. We also use AI to help us optimize and ensure we reach the highest quality patients.

This combination of quality, scale, and intent to act is what’s truly driving results where it matters most: conversion and ROI.

Proof in the Performance

For a leading pharma manufacturer, we’ve seen superior performance across multiple brands spanning therapeutic areas from oncology to neurology, GI conditions to rare disease. Our direct media programs are outperforming other endemic partners because we are able to reach our engaged patients everywhere they are, in the moments they are actively seeking solutions.

Here’s a look at how our optimization strategy impacted performance in 2025 across diverse conditions (source: Crossix):

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Metastatic Breast Cancer (mBC)

  • Program Goals: Engage mBC patients through a curated content experience on AdvancedBreastCancer.net and retarget at scale across the web
  • Health Union Performance: #1 endemic performer for diagnosed reach (more than double the #2 publisher), cost per diagnosed reach (most efficient on plan), and conversion to brand

Migraine

  • Program Goals: Educate diagnosed audiences about acute and preventative treatment on Migraine.com, and retarget at scale across the web
  • Health Union Performance: #1 endemic performer for diagnosed reach (highest reach at less than half the cost of the #2 performer), cost per diagnosed reached, audience quality (only partner to meet benchmarks), conversions, and cost per conversion

IBD

  • Program Goals: Connect with advanced ulcerative colitis (UC) patients looking to switch treatment on InflammatoryBowelDisease.net, and retarget at scale across the web
  • Health Union Performance: #1 highest audience quality of all endemic partners (with over double the targeting multiple of the #2 performer), success of this pilot led to a significant brand investment

Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

  • Program Goals: Empower diagnosed ATTR-CM patients to advocate for treatment by aligning with content across Health Union’s heart health communities, and retarget at scale across the web
  • Health Union Performance: #1 highest audience quality (over double benchmarkers) and #1 highest diagnosed reach out of all endemic partners

The Power of Authentic Content Combined with Scale

Ultimately, we aren’t just offering data. We are pairing data-driven targeting with powerful, authentic content. Patients are engaging in our communities, reading articles written by patients, for patients, and making connections that help them make better treatment decisions. No other endemic or community partner is achieving this combination of authenticity and measurable results.

The success of these programs has shown that our value extends far beyond our communities, delivering the highest on-plan scale, quality, efficiency, and conversions—results our competitors simply haven’t been able to replicate. We’ve built the infrastructure, and we can deliver these results now.

It’s time to change the way you think about community. This is your chance to put your brand in front of industry-leading content and solutions-seeking audiences in the key moments they are ready to make critical health decisions.

Learn more about Health Union’s award-winning community activation solutions: health-union.com/community-sponsorships

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